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galectin 3 nlrp3 il 1β signaling pathway  (Galectin Therapeutics)

 
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    Galectin Therapeutics galectin 3 nlrp3 il 1β signaling pathway
    Galectin 3 Nlrp3 Il 1β Signaling Pathway, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/galectin+3+pathway/pm42105955-102-47-47
    Average 86 stars, based on 1 article reviews
    galectin 3 nlrp3 il 1β signaling pathway - by Bioz Stars, 2026-10
    86/100 stars

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    other:

    Article Title: Heart failure subtype after acute kidney injury.
    Article Snippet: Acute Kidney Injury Induces Remote Cardiac Damage and Dysfunction Through the Galectin-3 Pathway.



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    Receiver operating characteristic (ROC) curves of serum YKL-40 and Galectin-3 for predicting proliferative vitreoretinopathy (PVR) development in rhegmatogenous retinal detachment (RRD) (a) ROC curve of serum YKL-40 demonstrating good discriminative performance for predicting PVR (AUC = 0.739, 95% CI = 0.621–0.856, p = 0.001; optimal cut-off = 26.9 ng/mL, sensitivity = 68.8%, specificity = 67.6%) (b) ROC curve of serum Galectin-3 showing moderate predictive accuracy (AUC = 0.643, 95% CI = 0.510–0.777, p = 0.045; optimal cut-off = 99.7 pg/mL, sensitivity = 62.5%, specificity = 58.8%) The diagonal line represents the reference line for random classification (AUC = 0.5)

    Journal: BMC Ophthalmology

    Article Title: Evaluation of serum YKL-40 and Galectin-3 as predictive biomarkers for proliferative vitreoretinopathy in rhegmatogenous retinal detachment: a prospective comparative study

    doi: 10.1186/s12886-025-04553-3

    Figure Lengend Snippet: Receiver operating characteristic (ROC) curves of serum YKL-40 and Galectin-3 for predicting proliferative vitreoretinopathy (PVR) development in rhegmatogenous retinal detachment (RRD) (a) ROC curve of serum YKL-40 demonstrating good discriminative performance for predicting PVR (AUC = 0.739, 95% CI = 0.621–0.856, p = 0.001; optimal cut-off = 26.9 ng/mL, sensitivity = 68.8%, specificity = 67.6%) (b) ROC curve of serum Galectin-3 showing moderate predictive accuracy (AUC = 0.643, 95% CI = 0.510–0.777, p = 0.045; optimal cut-off = 99.7 pg/mL, sensitivity = 62.5%, specificity = 58.8%) The diagonal line represents the reference line for random classification (AUC = 0.5)

    Article Snippet: Future research integrating paired serum and vitreous analyses, longitudinal follow-up, and targeted inhibition of YKL-40 or Galectin-3 pathways could clarify whether these biomarkers act as active mediators or downstream indicators of fibrosis.

    Techniques: